
This Spicy Mexican Casserole has been my go-to comfort meal for years when I need to feed a crowd with minimal fuss and maximum flavor. The combination of crunchy tortilla chips, seasoned beef, and melty cheese creates the perfect balance of textures that keeps everyone coming back for seconds.
I first made this casserole for a neighborhood potluck where I had little time to prepare something impressive. Not only did it disappear within minutes, but three different people asked for the recipe before the night was over.
Ingredients
- Ground beef: Provides the hearty base for this casserole. Choose 80/20 blend for best flavor
- Diced onion: Adds aromatic sweetness when cooked with the beef
- Rotel tomatoes with green chilies: Bring the perfect amount of heat and acidity
- Cream of mushroom soup: Creates a rich binding sauce without extra work
- Cream of chicken soup: Adds depth and creaminess to every bite
- Canned corn: Provides sweet pops of texture throughout the dish
- Black beans: Add protein and fiber making this a complete meal
- Tortilla chips: Create both a crunchy base and topping for textural contrast
- Mexican cheese blend: Melts beautifully for that perfect cheese pull
- Sour cream: Adds tanginess and helps cool the spice level
- Garlic powder: Infuses the entire dish with savory notes
- Chili powder: Brings authentic Mexican warmth without overwhelming heat
- Cumin: Adds that distinctive earthy flavor essential to Mexican cuisine
- Fresh cilantro: Brightens the finished dish with herbaceous notes
Step-by-Step Instructions
- Preheat Oven:
- Set your oven to 350°F and take a moment to lightly grease your baking dish. This temperature allows everything to heat through without burning the chips on top.
- Brown the Meat:
- Cook ground beef with the diced onions over medium heat until no pink remains. This should take about 8 minutes. Be sure to break the meat into small crumbles as it cooks for the best texture throughout the casserole.
- Create the Flavor Base:
- Add all your canned ingredients and spices to the meat mixture. The combination of the creamy soups with the acidic tomatoes creates a perfect sauce consistency. Make sure to gently fold everything together until evenly distributed.
- Layer the Base:
- Spread half your crushed tortilla chips across the bottom of your baking dish. Don’t crush them too finely; you want some substantial pieces for texture.
- Add the Filling:
- Pour your entire meat mixture over the chip base. Use a spatula to spread it into an even layer reaching all corners of the dish.
- Create the Topping:
- Scatter the remaining crushed chips over the meat layer followed by an even blanket of shredded cheese. The cheese will form a protective layer that keeps the chips underneath from becoming too soggy.
- Bake to Perfection:
- Place in your preheated oven for exactly 25 to 30 minutes. You’ll know it’s done when the cheese is completely melted with light golden spots and the edges are bubbling.
- Rest and Serve:
- Let the casserole rest for 5 minutes before serving. This crucial step allows the layers to set so your servings stay intact when plated.

My absolute favorite part of this recipe is the contrast between the crunchy tortilla chips and the creamy filling. My son once called it nacho casserole when he was five, and the name stuck around our house for years despite my attempts to give it a more sophisticated title.
Make It Your Own
This casserole welcomes personalization based on your tastes and what you have available. For a spicier version, add a diced jalapeño with the onions or use hot Rotel tomatoes. If you’re looking for a milder option, substitute regular diced tomatoes and reduce the chili powder by half. Ground turkey works beautifully as a lighter alternative to beef, though I recommend adding a tablespoon of olive oil when browning to maintain moisture.
Storage and Leftovers
This casserole stays good in the refrigerator for up to 4 days when stored in an airtight container. The flavors actually improve overnight as they have time to meld together. To reheat, cover with foil and warm in a 325°F oven for about 20 minutes until heated through. For single servings, microwave for 2 minutes, stopping halfway to stir. The texture of the chips will soften somewhat upon reheating, but the flavor remains delicious.

Serving Suggestions
Turn this casserole into a complete fiesta by serving it with simple accompaniments. A fresh green salad with cilantro lime dressing provides a refreshing contrast to the rich casserole. Set out bowls of additional toppings like diced avocado, extra sour cream, sliced jalapeños, and lime wedges so everyone can customize their plate. For beverages, nothing complements this dish better than a classic margarita for adults or a refreshing horchata for everyone.
The History Behind the Name
The term white trash casserole might raise eyebrows, but it belongs to a category of comfort foods that emerged in mid 20th century America when convenience ingredients became widely available. These casseroles typically feature canned soups, prepackaged ingredients, and minimal preparation while delivering maximum comfort and flavor. This particular version has evolved over decades to incorporate Mexican flavors that American palates have come to love, creating a fusion dish that honors both culinary traditions in a deliciously unpretentious way.
Frequently Asked Questions
- → Can I use a different type of meat?
Yes, you can substitute ground beef with ground turkey, chicken, or plant-based meat alternatives for a unique twist.
- → Can I make this casserole ahead of time?
Yes, you can prepare the casserole up to the baking step, cover it, and refrigerate for up to 24 hours before baking.
- → What other toppings can I add?
Feel free to add sliced jalapeños, diced avocado, or a squeeze of lime for extra flavor and texture.
- → Can I make this dish vegetarian?
Replace the ground beef with beans or a plant-based protein and ensure the soups used are vegetarian-friendly.
- → How do I store leftovers?
Store leftover casserole in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave.